Work Package | 2
Reference Measurement Procedures and higher-order methods to support genomic Reference Measurement Systems development
Aims
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to develop and evaluate nucleic acid amplification-based measurement procedures for key cancer biomarkers
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to develop and evaluate methods for the quantification of total DNA and quantification of DNA molecules of specified fragment size range or quality which would be suitable for value assignment of calibrators for end-user methods
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to apply sequencing technologies and methods as Reference Measurement Procedures approaches for sequence identity
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to establish the reproducibility of candidate Reference Measurement Procedures and review the adequacy of Measurement Uncertainty estimation
Work packages
Reference Measurement Systems to support validation and quality assurance of genomic profiling IVDs
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Creating impact
Reference Measurement Procedures and higher order methods to support genomic Reference Measurement Systems development
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Management & coordination
Reference Material and External Quality Assessment material development and SI-traceable characterisation frameworks to support genomic Reference Measurement Systems development and External Quality Assessment schemes
Measurement uncertainty frameworks to support genomic reference measurement systems
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