Reference Measurement Procedures and higher-order methods to support genomic Reference Measurement Systems development

to develop and evaluate nucleic acid amplification-based measurement procedures for key cancer biomarkers

to develop and evaluate methods for the quantification of total DNA and quantification of DNA molecules of specified fragment size range or quality which would be suitable for value assignment of calibrators for end-user methods

to apply sequencing technologies and methods as Reference Measurement Procedures approaches for sequence identity

to establish the reproducibility of candidate Reference Measurement Procedures and review the adequacy of Measurement Uncertainty estimation