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GenomeMET Work Package 3

Work Package | 3

Reference Material and External Quality Assessment material development and SI-traceable characterisation frameworks to support genomic Reference Measurement Systems development and External Quality Assessment schemes

Aims

  • to select genetic reference/External Quality Assessment materials to improve the reproducibility and comparability of genomic cancer profiling workflows

  • to develop novel reference material to support the comparability of genomic profiling workflows

  • to characterise and assign an SI-value to reference/External Quality Assessment materials/novel materials

  • to investigate routes for assessing commutability

  • to study pre-analytical quality control performance and analytical/whole workflow performance

  • to identify components needed for a framework for SI-traceable value assignment and commutability assessment of reference/External Quality Assessment materials to support genomic profiling workflows

Work packages

Reference Measurement Systems to support validation and quality assurance of genomic profiling IVDs

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Creating impact

Reference Measurement Procedures and higher order methods to support genomic Reference Measurement Systems development

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Management & coordination

Reference Material and External Quality Assessment material development and SI-traceable characterisation frameworks to support genomic Reference Measurement Systems development and External Quality Assessment schemes

Measurement uncertainty frameworks to support genomic reference measurement systems

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