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GenomeMET Work Package 3

Work Package | 3

Reference Material and External Quality Assessment material development and SI-traceable characterisation frameworks to support genomic Reference Measurement Systems development and External Quality Assessment schemes

Aims

  • to select genetic reference/External Quality Assessment materials to improve the reproducibility and comparability of genomic cancer profiling workflows

  • to develop novel reference material to support the comparability of genomic profiling workflows

  • to characterise and assign an SI-value to reference/External Quality Assessment materials/novel materials

  • to investigate routes for assessing commutability

  • to study pre-analytical quality control performance and analytical/whole workflow performance

  • to identify components needed for a framework for SI-traceable value assignment and commutability assessment of reference/External Quality Assessment materials to support genomic profiling workflows

Work packages

Reference Measurement Systems to support validation and quality assurance of genomic profiling IVDs

Creating impact

Reference Measurement Procedures and higher order methods to support genomic Reference Measurement Systems development

Management & coordination

Reference Material and External Quality Assessment material development and SI-traceable characterisation frameworks to support genomic Reference Measurement Systems development and External Quality Assessment schemes

Measurement uncertainty frameworks to support genomic reference measurement systems

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